I've heard that running with weights is a bad idea. Most of what I've read online (for example, this) seems to suggest unequivocally that weights on your legs are a serious health risk, but there seems to be a little less consensus about weights held in your hands.
My assumption was that it would be good for toning my shoulders and arms. I had been running with 450 gm weights for a few years- holding them in my hand, not around my wrist, usually between 7 and 15 km (at about a 5 min/km pace). But after reading about it online I decided to stop temporarily, even though I hadn't experienced any negative side effects.
I'd appreciate links/evidence one way or the other, preferably not just anecdotal.