Examine.com concludes that,
For maximal stimulation of muscle protein synthesis, aim for a per-meal dose of quality protein (such as can be found in meat, eggs, and dairy) of 0.4–0.6 g/kg [and immediately after resistance training]. Higher doses will not be wasted and are probably necessary when eating mixed meals that contain a variety of protein sources.
You may have heard that if you eat more than 30 grams of protein in one sitting, the “excess” will pass undigested, but that’s just a myth. It is however true that spreading your protein intake over a few meals, making sure that you meet your desirable minimal protein intake per meal with each meal, will generally result in greater lean mass and strength. A pragmatic review article suggests that, to maximize their lean mass, active adults should consume 1.6–2.2 g/kg/day spread across four meals (0.40–0.55 g/kg/meal).
After compiling various studies, fitness coach Jeff Nippard concludes that muscles can absorb more protein,
- in individuals with more muscle
- when more muscle is trained (whole body vs. legs)
- in older individuals, due to anabolic resistance
Intermittent fasters don't seem to be affected by their feeding schedule, and literature confirms it (6:05 in the video), but the study quality was low, and they used low total daily protein amounts. The body has an unlimited capacity to absorb amino-acids, but how much is utilized for muscle synthesis, is different. Absorbed protein may also limit muscle protein breakdown. Optimally, target 1g/lb of body mass, spaced over 4-5 meals.