GVT is German volume training where 10 sets of 10 of a compound movement is done. I am in doubt because such high rep is more like endurance work as I have learnt from various sources.
Yes, it will. GVT is extremely high volume, not high rep. 100 reps of any exercise in a single set would generally be considered endurance training, however breaking them down into sets with rest in between allows much heavier weights to be used, which is why when discussing rep numbers as a measure of intensity, we only count the number of reps in a single set.
E.g. Take a lifter with a 1RM squat of 140kg. They might be able to do 25 reps at 80kg. They might also be able to 5 sets of 5 at 110kg. Both the 25-rep (1x25@80kg) and the 5-rep (5x5@110kg) workouts have the same volume, but the 5-rep workout has much higher intensity and tonnage. (Tonnage is volume multiplied by intensity.) So the 25-rep workout could be considered endurance work, whereas the 5-rep workout is definitely strength work, despite them having the same volume.
A 2017 study into the effectiveness of GVT found that it does produce increases in strength and muscle mass, though it was actually less effective than only doing 5 sets of 10 reps. Unfortunately the study abstract doesn't indicate what level of training the test subjects had been exposed to prior to the study, which is problematic, as untrained subjects will gain strength and size when exposed to literally any training program.
This blog post also does a decent job of explaining the results of the above study.
From what i understood from Barbell Medicine seminar, there are two considerations: 1. Volume is primary driver of hypertrophy when you lift in 60-80% range. 2. You need to balance your workout with recovery. That is you might get so fatigued from 10x10 that you won’t be able to do next workout. In such case it would be prescribed to do two days, 5x10 each
You need to consider that single workout at post-novice stage doesn’t change much. You will progress from week to week or even from month to month. Thus, it is essential to train consistently.